Publications

Complete list of publications at PubMed

Patil N. Y., Rus I., Joshi A. D. Role of ERK1/2 signaling in cinnabarinic acid-driven stanniocalcin 2-mediated protection against alcohol-induced apoptosis, Journal of Pharmacology and Experimental Therapeutics, 387(1):111-120, 2023

Patil N. Y., Friedman J.E., Joshi A. D. Role of hepatic aryl hydrocarbon receptor in non-alcoholic fatty liver disease, Receptors, 2(1)1-15, 2023

Patil N. Y., Rus I., Downing E., Mandala A., Friedman J. E., Joshi A.D. Cinnabarinic acid provides hepatoprotection against non-alcoholic fatty liver disease, Journal of Pharmacology and Experimental Therapeutics, 383(1):32-43, 2022

Joshi A. D.#, Thinakaran G., Elferink C. Cinnabarinic acid-induced stanniocalcin 2 confers cytoprotection against alcohol-induced liver injury, Journal of Pharmacology and Experimental Therapeutics, 381(1):1-11, 2022 (#corresponding author)

Patil N. Y., Tang H., Rus I., Zhang K., Joshi A. D. Decoding cinnabarinic acid specific stanniocalcin 2 induction by aryl hydrocarbon receptor, Molecular Pharmacology, 101(1):45-55, 2022

Girer N., Rontoyanni V. G., Joshi A. D., Patrikeev I., Murton A. J., Porter C., Motamedi M., Elferink C. J. Journal of Pharmacology and Experimental Therapeutics, PMID: 34074713, 2021

Joshi A. D. New Insights into Physiological and Pathophysiological Functions of Stanniocalcin 2, Frontiers in Endocrinology, 11(172) 1 – 8, 2020

Joshi A. D.#, Hossain A., Elferink C. J. Epigenetic Regulation by Agonist-Specific Aryl Hydrocarbon Receptor Recruitment of Metastatic Associated Protein 2 Selectively Induces Stanniocalcin 2 Expression, Molecular Pharmacology, 92(3): 366-374, 2017 (#corresponding author)

Lee C. S., Hanna A. D., Dagnino-Acosta A., Joshi A. D., Wang H., Knoblauch M., Xia Y., Georgiou D. K., Xu J., Long C., Amano H., Reynolds C., Dong K., Lagor W., Rodney G. G., Sahin E., Hamilton S. L. A Potential Intervention for an RyR1 Myopathy Associated with a Pore Blocking Mutation, Nature Communications, 8:14659, 2017

Wright E. J.*, Pereira de Castro K.*, Joshi A. D.*, Elferink C. J. New insights into canonical and non-canonical aryl hydrocarbon receptor signaling pathways, Current Opinion In Toxicology, 2:87-92, 2017 (* Equal First Author Contribution)

Gaziova I., Jackson D., Boor P. J., Carter D., Cruz-Monserrate Z., Elferink C. J., Joshi A. D., Kaphalia B., Logsdon C. D., Pereira de Castro K., Soong L., Tao X., Qiu S., Elferink L. A. The MET Receptor Tyrosine Kinase Confers Repair of Murine Pancreatic Acinar Cells following Acute and Chronic Injury. PLoS One, 11(10), 2016

Joshi A. D., Lichti C. F., Mustafa M. G., Elferink C. J. Homocitrullination is a novel histone H1 epigenetic mark dependent on aryl hydrocarbon receptor recruitment of carbamoyl phosphate synthase 1, Journal of Biological Chemistry, 290(46) 27767 – 27778, 2015

Joshi A. D., Carter D. E., Harper T. A., Jackson D., Elferink C. J. Aryl hydrocarbon receptor dependent stanniocalcin 2 induction by cinnabarinic acid provides cytoprotection against ER and oxidative stress, Journal of Pharmacology and Experimental Therapeutics, 353(1) 201 – 212, 2015

Jackson D. P., Joshi A. D., Carter D. E., Elferink C. J. Ah receptor pathway intricacies; signaling through diverse protein partners and DNA-motifs, Toxicological Research, 4, 1143 – 1158, 2015

Lee C. S., Georgiou D. K., Dagnino-Acosta A., Xu J., Ismailov I., Knoblauch M., Monroe T. O., Ji R., Hanna A. D., Joshi A. D., Long C., Oakes J., Tran T., Corona B. T., Lorca S., Ingalls C. P., Narkar V. A., Lanner J. T., Bayle J. H., Durham W. J., Hamilton S. L. Ligands for FKBP12 increase Ca2+ influx and protein synthesis to improve skeletal muscle function, Journal of Biological Chemistry, 289(37) 25556 – 25570, 2014

Jackson D. P., Li H., Mitchell K. A., Joshi A. D., Elferink C. J. Role of Ah receptor mediated suppression of liver regeneration through NC-XRE driven p21Cip1 expression, Molecular Pharmacology, 85(4) 533 – 541, 2014

Harper T. A., Joshi A. D., Elferink C. J., Identification of stanniocalcin 2 as a novel aryl hydrocarbon receptor target gene, Journal of Pharmacology and Experimental Therapeutics, 344(3) 579 – 588, 2013 

Wilson S. R.*, Joshi A. D.*, Elferink C. J., The tumor suppressor Kruppel-Like factor 6 is a novel aryl hydrocarbon receptor DNA binding partner, Journal of Pharmacology and Experimental Therapeutics, 345(3): 419 – 429, 2013 (* Equal First Author Contribution)

Lanner J. T., Georgiou D. K., Dagnino-Acosta A., Ainbinder A., Cheng Q., Joshi A. D., Chen Z., Yarotsky V., Oakes J. M., Lee C. S., Monroe T., Santillan A., Dong K., Goodyear L., Ismailov I., Dirksen R. T., Hamilton S. L., AICAR prevents heat-induced Malignant Hyperthermia in RyR1 mutant mice independent of AMPK activation, Nature Medicine, 18 (2) 244 – 251, 2012

Lanner J. T., Georgio D. K., Joshi A. D., Hamilton S. L. Ryanodine receptors: structure, expression, molecular details and function in calcium release, Calcium Signaling, Cold Spring Harbor Perspectives in Biology, 2 (11) 1 – 21, 2010

Pajor A.M., Sun N. N., Joshi A. D., Randolph K. M., Transmembrane helix 7 in the Na+/dicarboxylate cotransporter 1 is an outer helix that contains residues critical for function, Biochimica et Biophysica Acta - Biomembranes, 1808 (6) 1454 – 61, 2010

Joshi A. D. and Pajor A. M., Identification of conformationally sensitive amino acids in Na+/dicarboxylate symporter (SdcS), Biochemistry, 48 (13) 3017 – 3024, 2009

Joshi A. D. and Pajor A. M., Role of conserved prolines in the structure and function of the Na+/dicarboxylate cotransporter 1, NaDC1, Biochemistry, 45 (13) 4231 – 4239, 2006